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Sobel said he hopes his study will end insurers' reluctance to pay for long-term use of fluconazole But if something goes out of kilter, they can multiply wildly Sometimes pregnancy, diabetes, antibiotics, steroids or a weakened immune system cause the overgrowth For the next six months, half took a weekly dose and half took lookalike dummy pills Jack D Diflucan costs up to $30 a pill - five times the price of the least expensive over-the-counter cream - though new generics are pushing down the price But up to 8 percent of all women get four or more of these infections a year, some as often as once a month The study was underwritten by Pfizer, which makes the fluconazole pill Diflucan Half the researchers and Eschenbach have financial ties to Pfizer or other drug companies Each got three fluconazole pills three days apart Eschenbach, chairman of the Department of Obstetrics and Gynecology at the University of Washington Medical Center One dose of a drug called fluconazole, or a week of nonprescription cream, can stop the itching, burning and discharge Three out of four women get at least one vaginal yeast infection sometime in their lives David A Yeasts are normal inhabitants of the body "Then it almost rules your life," said Dr At the end of six months, 91 percent of those on fluconazole were clear of the yeast, compared with 36 percent of the placebo group The study looked at 387 women suffering from recurrent Candida albicans, the most frequent cause Sobel, chief of infectious disease at Wayne State University School of Medicine in Michigan Regular Pills May Thwart Yeast Infections JANET McCONNAUGHEY Associated Press Women who get lots of painful yeast infections can safely ward them off with a weekly pill, the largest study on the subject has found Regular, preventive doses of an antifungal drug for six months dramatically cut the number of episodes The study of whether fluconazole works as a preventive treatment was reported in Thursday's New England Journal of Medicine and was led by Dr But it wasn't a cure: Over time, infections recurred in many women During the next six months, nearly 43 percent of the women who had taken fluconazole stayed disease-free, compared with 22 percent of those on the placebo Sometimes the cause is unknown After the ruling, a fiery-eyed Trevi called the judge "corrupt Trevi's chief accuser is Karina Yapor, a 17-year-old girl from Chihuahua whose parents let her join Trevi's entourage five years ago Trevi's lawyers had hoped the judge would dismiss some or all three charges or release her on bail The 34-year-old Trevi was extradited from Brazil to Mexico on Saturday, and is being held in a maximum security prison in Chihuahua, 760 miles northwest of Mexico City " Accusations that Trevi and Andrade were sexually abusing girls who joined their entourage began to surface in 1998 Trevi fought extradition for three years, but last month she suddenly requested to return to her homeland, saying she wanted the chance to defend herself in court The pair disappeared a year later, sparking a worldwide manhunt Trevi, nicknamed 'Mexico's Madonna," has been accused of recruiting adolescent girls for live-in musical training that included sex with her manager and ex-husband, Sergio Andrade Trevi, Andrade and a backup singer were arrested in Rio de Janeiro in January 2000 Judge Orders Trevi to Remain in Jail Dec 24, 8:35 PM EST A judge denied Mexican pop diva Gloria Trevi's request for bail Tuesday and ordered her to remain in prison while being tried for rape, kidnapping and corruption of minors Yapor abandoned a baby in Spain in 1998, claiming Andrade was the father |
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